| Evidence 2011 - Wednesday 26th October |
| 08:00 | | Breakfast Session Karen Ritchie, Healthcare Improvement Scotland
Roberta James, Scottish Intercollegiate Guidelines Network (SIGN)
Ann Lee, Scottish Medicines Consortium
Karen Macpherson, Scottish Health Technologies Group

Breakfast Session
Session: Not quite NICE, but thrifty and nifty: The Scottish Approach to developing advice and guidance
26th Oct 2011 - 08:00
Karen Ritchie, Healthcare Improvement Scotland
Roberta James, Scottish Intercollegiate Guidelines Network (SIGN)
Ann Lee, Scottish Medicines Consortium
Karen Macpherson, Scottish Health Technologies Group

We will present the approach taken to developing clinical guidelines and HTA advice for NHSScotland on new medicines and other technologies. We will discuss how the groups involved in this work share knowledge and collaborate to avoid conflicting advice and are working together to address some of the key challenges in healthcare provision in the 21st century.
What single idea from your lecture, will make the biggest impact on healthcare today?
That high quality advice and guidance on clinical management and health technologies can be developed in way that is cost effective and responsive to practitioners’ needs.
Learning outcomes – after this session, participants will be able to
- Describe how NHSScotland develops and delivers evidence based advice and guidance
- Understand some of the challenges of developing such guidance for the health service in Scotland
- Identify differences in approach of the NHS in England and Scotland to similar problems
Experience Level
Beginner, though some understanding of health technology assessment and guideline development would be useful.
| Breakfast Session Speakers TBA

Breakfast Session
Session: Session information coming soon
26th Oct 2011 - 08:00
Speakers TBA

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| 09:00 | K6 Introduction: Fighting your inner quack Ben Goldacre
Award-winning writer, broadcaster, and medical doctor, writer of the weekly Guardian Bad Science column, and author of the book 'Bad Science'
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| 09:10 | K7 David Spiegelhalter
Winton Professor of the Public Understanding of Risk, University of Cambridge
K7
Keynote: Communicating risk and uncertainty
David Spiegelhalter
Winton Professor of the Public Understanding of Risk, University of Cambridge
26th Oct 2011 - 09:10
Shared decision-making requires a shared understanding of the possible benefits and harms of different options. I will look at the ways in which the chances of different outcomes are communicated to patients, emphasising the use of multiple representations that can adapt to individual needs, tastes and abilities. Acknowledging uncertainties about the chances themselves may only be appropriate for some patients. Transparent communication to individuals may not have the consequences desired by those concerned with the health of the population.
Learning outcomes – after this session, participants will be able to:
- Identify options for communicating risk
- Accept range of needs and understanding of patients
- Know about the advantages and disadvantages of different representations
Aimed at which audience
All
Experience level
Beginner
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| 09:40 | K8 Mark Gibson
Director, Center for Evidence Based Policy, Oregon Health and Science University
K8
Keynote: Evidence, Outreach and Governance Lessons from the American States
Mark Gibson
Director, Center for Evidence Based Policy, Oregon Health and Science University
26th Oct 2011 - 09:40
The Oregon Health Plan pioneered using clinical value and public participation to shape healthcare coverage. In two decades the science of research synthesis and the nature of public and industry advocacy have changed significantly. Multiple states now work together to obtain actionable evidence and to support its use in policy. Their experience includes improved care and cost savings. It also includes inefficiency from devolved decision making and difficulties finding the public interest in democratic processes.
What single idea will make the biggest impact on healthcare today?
"Health care democratization” has a utopian rhetorical ring, but in reality it may fall short of the ideal it evokes.
Learning outcomes – after this session, participants will be able to:
- Identify how the science of research synthesis and the conduct of healthcare advocacy have changed over 20 years.
- Understand how some American states have evolved their policy making to address the challenges presented by changes in research and advocacy.
- Identify lessons learned from the US experience that could be useful to national health systems as they debate issues of governance devolution and democratization of health system decision making.
Aimed at which audience
Anyone concerned with health system performance, system governance, and stakeholder engagement
Experience level
Any level
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| 10:10 | K9 Philippe Duclos
Health Adviser Department of Immunization, Vaccines and Biologicals, WHO
K9
Keynote: Creating global guidance for vaccination and immunization
Philippe Duclos
Health Adviser Department of Immunization, Vaccines and Biologicals, WHO
26th Oct 2011 - 10:10
The World Health Organization (WHO) has recently adjusted its policy making processes for vaccines and immunization. This includes an enlarged consultation process to generate evidence-based recommendations, ensuring the transparency of the decision making process, and improving communications.
This presentation will describe the process and challenges of the development of immunization policy recommendations at the global level through the Strategic Advisory Group of Experts on immunization and the process leading to the publication of WHO position papers on vaccine use. A particular focus will be given to the challenges of using GRADE, updating recommendations and dealing with emergency situations and situations where there is a paucity of data.
What single idea will make the biggest impact on healthcare today?
Facilitate the exchange of information between immunization technical advisory committees and/or One ounce of prevention is better than one pound of cure.
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| 10:40 | Refreshments & poster viewing |
| 11:10 | D1 Mike Kelly
Director of the Centre of Public Health Excellence, NICE
D1
Session: Evidence for value and efficiency
Mike Kelly
Director of the Centre of Public Health Excellence, NICE
26th Oct 2011 - 11:10
This paper explains the method for deriving value for money for public health interventions to prevent disease. It demonstrates he significant savings that can accrue from public health activity.
What single idea will make the biggest impact on healthcare today?
In the face of decline in available budgets for health care the spend on prevention must be preserved.
Learning outcomes
- Apply principles of health economics to public health activity.
- Understand the methods used by NICE to develop measures of cost effectiveness.
- Think about the deployment of public health resources at local level.
Aimed at what audience
CEOs, local government, public health practitioners.
Experience level
Beginners/ experienced
Juan Cabello
Director, CASP España
D1
Session: Critically appraising evidence in knowledge translation - challenges for the future
Juan Cabello
Director, CASP España
26th Oct 2011 - 11:10
Knowledge translation is essential to promote effective care and eliminate the ineffective. A huge effort has been made to build evidence, publish results and promote the transparency and quality of health research. Although critical appraisal is the next step in knowledge translation, it has received less attention.
Current critical appraisal tools and the models of reading are discussed in this session, emphasizing the foreseeable changes induced by the new technologies and suggesting adaptation mechanisms.
What single idea will make the biggest impact on healthcare today?
Critical appraisal is the meeting point between the written evidence and its potential application. As written evidence evolves continuously, critical appraisal should develop adaptive strategies.
Learning outcomes
- To identify the problems in reading the evidence and pre-appraised evidence.
- To know the strengths and weaknesses of the current critical appraisal tools.
- To predict problems related to the development of new information technologies in health.
Aimed at which audience
General audience: health workers, patients, citizens, or anyone interested in knowledge translation.
Stefan Lange
Deputy Director, Institute for Quality and Efficiency in Health Care
D1
Session: (New) Challenges of health technology assessment
Stefan Lange
Deputy Director, Institute for Quality and Efficiency in Health Care
26th Oct 2011 - 11:10
Decisions on the reimbursement of medical services are becoming more and more difficult for several reasons (e.g. increasing financial constraints). Therefore, the importance and requirements of health technology assessment are steadily increasing. Current challenges with regard to the assessment of medical interventions are: the validity of surrogates, the interpretability of indirect and mixed treatment comparisons, the appropriate evaluation of diagnostic procedures, and the criteria and quantification of effects as a basis for judging 'relevance'.
What single idea will make the biggest impact on healthcare today?
Decisions on reimbursement should be based on patient-relevant evidence that is as unbiased as possible
Learning outcomes – after this session, participants will be able to:
To understand the current challenges of health technology assessment
Aimed at which audience
Senior managers
Experience level
Experienced
Chaired by
Doug Altman
Director, Centre for Statistics in Medicine, Oxford
Chaired by Doug Altman
Director, Centre for Statistics in Medicine, Oxford
| D2 Gill Gyte
NCT and Cochrane Collaboration Consumer Network
D2
Session: Using consumer information to inform guidelines
Gill Gyte
NCT and Cochrane Collaboration Consumer Network
26th Oct 2011 - 11:10
Introduction to consumer input into clinical guidelines
Reporting on observations and suggestions arising from personal experiences of being a consumer representative on three clinical guideline development groups
Discussing the need for a process for using consumer information to inform guidelines and looking at what such a process might involve
What single idea will make the biggest impact on healthcare today?
Ensure that guideline development groups include consumer information by providing a robust process which ensures good quality evidence based in information
Learning outcomes – after this session, participants will be able to:
Ensure that guideline development groups include consumer information by providing a robust process which ensures good quality evidence based in information
Aimed at which audience
All those involved in developing and using guidelines
Experience level
All levels
Sally Crowe
James Lind Alliance and Crowe Associates Ltd
D2
Session: Involving the public in healthcare research debates – single or shared voice?
Sally Crowe
James Lind Alliance and Crowe Associates Ltd
26th Oct 2011 - 11:10
- Describing James Lind Alliance and UK DUETs
- Collecting and publishing uncertainties in the effects of treatments – from multiple perspectives
- Describing a process for shared priorities in health care research
- The role of Priority Setting Partnerships of patients and clinicians, and their impact on research agendas
- Examples of methods used and outcomes recorded
- What happens when patients and clinicians do, and don’t agree on priorities
- The impact of shared priorities on funded clinical research
What single idea will make the biggest impact on healthcare today?
Democratizing clinical research – a process for producing transparently prioritized research questions that reflect patient/carer and clinical and research perspectives on ongoing uncertainties in healthcare.
Aimed at which audience
Anyone with a stake in clinical research, more relevance to clinicians and patients than managers
D2
Session: How does patient involvement make a difference to clinical research?
26th Oct 2011 - 11:10
Defining patient involvement in research.
The benefits of patient involvement:
- impact on research design
- impact on the ethical acceptability of research
- impact on recruitment
- impact on data quality
The challenges of patient involvement:
- convincing researchers to involve patients
- building capacity amongst patients
What single idea will make the biggest impact on healthcare today?
Make high quality patient involvement a condition for funding clinical research.
Learning outcomes – after this session, participants will be able to:
- Describe how patient involvement has had a positive impact on clinical research
- Reflect on the training and support needed by researchers and patients to work together on research
Aimed at which audience
Anyone with a stake in clinical research, more relevance to clinicians and patients than managers
Experience level
Not relevant
Chaired by
Sir Iain Chalmers
James Lind Initiative, Oxford, UK
Chaired by Sir Iain Chalmers
James Lind Initiative, Oxford, UK
| D3 A showcase and practical demonstration of new innovations and technology in evidence based healthcare
Implementing EBM, Quality Improvement and the move to Practice Based Evidence
Dr Andrew Jones, Clinical Engagement Specialist
Demonstration of Audit+
Speakers TBC
Demonstrating the new EBM Application
Speakers TBC
D3
Session: INNOVATION ROOM
26th Oct 2011 - 11:10
A showcase and practical demonstration of new innovations and technology in evidence based healthcare
11:10 - BMJ Group
Implementing EBM, Quality Improvement and the move to Practice Based Evidence
Dr Andrew Jones, Clinical Engagement Specialist
11:35 - BMJ Informatica Systems
Demonstration of Audit+
Speakers TBC
12:00 - Oxford Centre for Evidence Based Medicine and BMJ Evidence Centre
Demonstrating the new EBM Application
Speakers TBC
Chaired by
Matthew Thompson
Deputy Director, Centre for Evidence-Based Medicine, University of Oxford
Chaired by Matthew Thompson
Deputy Director, Centre for Evidence-Based Medicine, University of Oxford
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| 12:30 | |
| 13:30 | E1 Gavin Yamey
Evidence to Policy initiative (E2Pi), Global Health Group, University of California San Francisco
E1
Session: The payoffs and pitfalls of evidence-based global health policymaking
Gavin Yamey
Evidence to Policy initiative (E2Pi), Global Health Group, University of California San Francisco
26th Oct 2011 - 13:30
One of the reasons why progress has been slow in achieving the maternal and child health Millennium Development Goals is the wide gap between evidence and practical policymaking. Why does this gap persist? This session explores some of the key reasons, including the poor global flow of evidence, the sociopolitical influences on policymakers, and the complex and poorly understood apparatus of policy implementation. It will also propose ways to narrow the “know-do” gap in global health.
What single idea will make the biggest impact on healthcare today?
“Globally, joining the dots between different sectors—nutrition, education, water, sanitation, and climate—could make the biggest impact upon health and healthcare.”
Learning outcomes - after the session, participants will be able to :
- To understand the factors that influence decision-making in global health
- To identify the key barriers to evidence-based policymaking in global health
- To identify some of the innovative ways in which these barriers can be overcome
Aimed at which audience
Anyone who works in global health, particularly public health professionals
Experience level
Beginners to masters level
Professor Martin Marshall
The Health Foundation
E1
Session: Evidence for implementing change
Professor Martin Marshall
The Health Foundation
26th Oct 2011 - 13:30
Implementing best practice across the health service in a sustainable way remains one of the biggest challenges facing practitioners, policy makers and academics. The science of improvement is a relatively new science in the health sector and one that complements the long established basic and clinical sciences. By developing partnerships between academics and practitioners and drawing on a wide range of academic disciplines, it has the potential to address the challenge of implementing best practice. In this presentation, Professor Marshall will explore the characteristics, current contribution and future direction of the science of improvement.
What single idea will make the biggest impact on healthcare today?
Only a new approach to science will address the challenge of implementation.
Learning outcomes – after this session, participants will be able to:
Have an understanding of the nature of the science of improvement and its potential to improve patient outcomes.
Aimed at which audience
All!
Experience Level
All
| E2
E2
Session: The impact of publishing research with open access
26th Oct 2011 - 13:30
Arguments for open access (OA):
- public money spent only to fund research, not to access it
- audience not limited by ability to pay
- makes evidence more accessible
- more author-centric and user-centric
- shifts the concept of impact from citations --> downloads/usage
Arguments against OA:
- quality vs quantity tradeoff?
- exacerbates publish or perish culture?
- end of the "reader"?
- threat to traditional journals?
Practicalities:
- funders' OA mandates and why they matter
- how open peer review and OA can work together
- various models of OA
What single idea will make the biggest impact on healthcare today?
“Developing the right evidence and getting it to the right people at the right time and place will make the biggest impact on healthcare.”
Learning outcomes – after this session, participants will be able to:
- to make more informed choices when deciding where to publish research
- to understand different concepts of the impact of research
- to understand more about peer review
Aimed at which audience
- researchers
- people who use the results of research in their daily work or teaching
Experience level
All
Jon Brassey
TRIP Database Ltd & Public Health Wales
E2
Session: What answering 10000+ clinical questions tells you about evidence
Jon Brassey
TRIP Database Ltd & Public Health Wales
26th Oct 2011 - 13:30
The presentation will explore question answering using an evidence-based approach. It will explore search, the nature of evidence and why both need to dramatically improve to help clinicians practice in an evidence-based manner. It will draw on the experience of running the TRIP Database and various clinical Q&A services.
What single idea will make the biggest impact on healthcare today?
Removing the barriers to using evidence, by making it easily available and clinically focused, will ensure care is evidence based.
Learning outcome – after this session, participants will be able to:
- Appreciate the need for clinically-focussed evidence
- Understand why search can be part of the problem as well as the answer
Aimed at which audience
General audience
Experience Level
Any
Chaired by
Ben Goldacre
Award-winning writer, broadcaster, and medical doctor, writer of the weekly Guardian Bad Science column, and author of the book 'Bad Science'
Chaired by Ben Goldacre
Award-winning writer, broadcaster, and medical doctor, writer of the weekly Guardian Bad Science column, and author of the book 'Bad Science'
| E3 A selection of rapid-fire presentations highlighting the best of evidence based research in the scientific community
E3
Session: RESEARCH SHOWCASE
26th Oct 2011 - 13:30
A selection of rapid-fire presentations highlighting the best of evidence based research in the scientific community
Chaired by
Doug Altman
Director, Centre for Statistics in Medicine, Oxford
Chaired by Doug Altman
Director, Centre for Statistics in Medicine, Oxford
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| 14:30 | Refreshments & poster viewing |
| 15:00 | F1 Tom Jefferson
Editor Cochrane Acute Respiratory Infections Group
F1
Session: Hayashi’s problem (what you read may not be what it seems)
Tom Jefferson
Editor Cochrane Acute Respiratory Infections Group
26th Oct 2011 - 15:00
Recent cases of exposure of sponsor bias overturning our understanding of important interventions (antipsychotics, riboxetine, vioxx, tamiflu) have shown that reliance on published material can be misleading and affected by reporting bias. However, only 10% of Cochrane reviews search for unpublished material. Using the story of the Cochrane review on Tamiflu as background, Tom will chart current efforts to develop methods for identifying and synthetising evidence from trials of important pharmaceuticals using regulatory-sourced material only.
(Funding: HTA(UK) programme Project 10.80.01 – Update and amalgamation of two Cochrane Reviews: neuraminidase inhibitors for preventing and treating influenza in healthy adults and children)
What single idea will make the biggest impact on healthcare today?
Access to unbiased and unspun clinical trial data
Learning outcomes
- Be aware of the limits of research synthesis and decision making based on published trial data
- Trust everything they read, after thorough verification
- Write to their MP to demand action from regulators to disclose all drug registration material in their keeping
Aimed at which audience
All healthcare workers
Experience level
Any
Dr Deb Cohen
Assistant Editor, BMJ
F1
Session: Left to their own devices (what evidence for medical devices?)
Dr Deb Cohen
Assistant Editor, BMJ
26th Oct 2011 - 15:00
In both the EU and the US, medical device regulation has come in for scrutiny recently. The MHRA has said that the evidence base for most devices is poor. But how do devices get onto the market? And how are clinicians and other healthcare decision makers able to make judgments on what they use and purchase? This workshop will look at some of the challenges facing clinicians and those trying to assess the evidence.
What single idea will make the biggest impact on healthcare today?
Transparency in decision making alongside access to clinical trial data.
Learning outcomes – after this session, participants will be able to:
- Learn about working collaboratively – researchers, journals and mainstream media
- Find out how to access data that might not be in medical journals – and find out about when it simply isn’t available
- Learn to question what you read
Aimed at which audience
All health workers
Experience level
Any
Chaired by
Fiona Godlee
Editor in Chief, BMJ
Chaired by Fiona Godlee
Editor in Chief, BMJ
| F2 Prof Ian Wall
Past President Faculty of Forensic and Legal Medicine
F2
Session: Ageing of bruising – what’s the evidence?
Prof Ian Wall
Past President Faculty of Forensic and Legal Medicine
26th Oct 2011 - 15:00
There has been much speculation as to the age of a bruise, particularly from doctors who work in Emergency Departments. This presentation will look at the research evidence on ageing of bruising and consider the impact this has on the judicial process.
What single idea will make the biggest impact on healthcare today?
Be very cautious when trying to age bruises!
Learning outcomes – after this session, participants will be able to:
- Understand the physiology of colour change in bruises.
- Understand the evidence base for ageing of bruises.
Aimed at which audience
Emergency Department, GPs, Forensic Physicians, Paediatricians
Experience level
All
2. Sexual Assault & Genital Injuries Chaired by Carl Heneghan
Director, Centre for Evidence-Based Medicine, University of Oxford
| F3 1. Using new technologies to deliver healthcare Lionel Tarassenko MA, DPhil, FREng, FIET
Chair in Electrical Engineering at Oxford University
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| 16:05 | Closing Reflections Fiona Godlee
Editor in Chief, BMJ
Carl Heneghan
Director, Centre for Evidence-Based Medicine, University of Oxford
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| 16:15 | K10 Dr Phil Hammond
GP, writer, broadcaster and comedian. Private Eye’s medical correspondent and occasional panelist on Have I Got News For You.
K10
Keynote: Sex, Sleep or Scramble?
Dr Phil Hammond
GP, writer, broadcaster and comedian. Private Eye’s medical correspondent and occasional panelist on Have I Got News For You.
26th Oct 2011 - 16:15
Phil reveals what goes through the mind of the doctor and will explore the evidence and answers to some of life’s quirkier medical queries.
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| 17:00 | |